Two different questions
"Does compression reduce quality" conflates two things: whether information is discarded, and whether you can see that it was.
Information: lossless formats discard none, lossy formats always discard some. That part is absolute and not a matter of settings.
Visibility: a completely different question, decided by how much was discarded, what the image contains, and how large it is displayed. A photograph at quality 80 has genuinely lost data and genuinely looks identical at the size anyone will view it.
Most arguments about this are people answering different questions.